Aspartate Aminotransferase (AST, GOT)
Catalogue Number: 306-10
Description
Product Name | Aspartate Aminotransferase |
Source | Human Liver |
Catalogue Number | 306-10 |
Purity | Purified |
Form | Lyophilized |
Activity | > 1 U/mg (Dimension® Clinical Chemistry System) |
Unit Definition | One unit will catalyze the transamination of one micromole of L-aspartate to alpha-ketoglutarate forming L-glutamate and oxaloacetate per minute at 37°C and pH 7.8. |
Protein | > 0.5 mg protein/mg (Coomassie) |
Specific Activity | Report in U/mg protein |
Contaminants | CK: < 1.0% ALT/GPT: < 2.0% LDH: < 10% Ammonia: < 0.01 micromole/mg |
Recertification | 3 years |
Storage | -20°C |
Synonyms | Aspartate Transaminase, Glutamate Oxaloacetate, AST, GOT, sGOT, AspAT, ASAT, AAT, serum glutamic oxaloacetic transaminase |
Molecular Weight | ~92,000 (Feliss and martinez-Carrion 1970) |
UNSPSC code | 51131907 |
CAS Number | 9000-97-9 |
E.C. Number | 2.6.1.1 |
Applications
Overview
Lee Biosolutions is a producer and supplier of human liver enzyme Aspartate Aminotransferase/Glutamate Oxaloacetate Transaminase (AST/GOT) for research and clinical diagnostic assays for liver disease.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
AST/SGOT is found in many tissues throughout the body, including the liver, heart, muscles, kidney, and brain. If any of these organs or tissues is affected by disease or injury, AST is released into the bloodstream. This means that AST isn't as specific an indicator of liver damage as ALT (also known as alanine aminotransferase, another type of enzyme found almost entirely in the liver).
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